Information
Kratom for Potential
Medicinal Uses
While Kratom has not been proven safe or effective for any medical purpose, Kratom has been used in traditional medicine in some countries, and many people who use Kratom report doing so self-medicate for pain, anxiety, depression, substance withdrawal. Studies in animal models suggest Kratom and related compounds potentially have other therapeutic properties, such anti depressant and pain relieving properties, that may warrant further study. Studies on Kratom nad Kratom compounds warrant further study as experimental treatments for substance use disorders, specifically opioid use disorder. Such treatments are urgently needed to help curb the drug overdose epidemic in the world.
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Suspected Health Benefits of Kratom
Kratom for Pain
Kratom may be effective for easing chronic pain, as it works by attaching to opioid receptors. One compound found in kratom, 7-hydroxymitragynine, is 13 times more potent than morphine. Although kratom targets opioid receptors just like morphine and codeine do, it is considered an atypical opioid. Kratom selectively inactivates specific signals, which may explain the more tolerable side effects compared to typical opioids.
Kratom for Mood Boosting
Kratom may have mood-enhancing effects. Some reports suggest that kratom may be an effective treatment for opioid addiction. Some people use it to help ease the withdrawal symptoms of morphine and ethanol. Early studies suggest that kratom may have potential as an antidepressant and a hunger suppressant. In one animal study, researchers determined that kratom lowers corticosterone levels in mice. Increased corticosterone levels are just one of the changes in brain chemicals that can be seen in depression. Furthermore, in another study with rats, kratom supplementation suppressed hunger by inhibiting the hypothalamus, the part of the brain responsible for appetite and cravings. More research on humans is needed to see if kratom has similar effects.
Kratom for Opiate Withdrawal
Some people have reported that kratom can help with self-treatment of opioid withdrawal symptoms. It has also been promoted as a remedy or cure for opioid addiction. But there’s no approved use of kratom for these purposes. Experts need to look deeper into this to understand if it can actually help with withdrawal.